Thymosin Alpha-1 is a synthetic peptide studied in laboratory research focused on immune signaling, cellular communication, and mechanisms involved in immune system regulation.
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Thymosin Alpha-1 Product Overview Thymosin Alpha-1, commonly abbreviated as Tα1 or TA1, is an N-terminally acetylated peptide composed of 28 amino acids. Its sequence corresponds to the first 28 amino-acid residues of prothymosin alpha. Each vial contains 10mg of lyophilized Thymosin Alpha-1 intended for controlled laboratory investigation of immune-related signalling pathways, cellular communication and peptide interactions within defined experimental systems. Product Specifications: Product name: Thymosin Alpha-1 Common abbreviations: Tα1 and TA1 Quantity per vial: 10mg Peptide length: 28 amino acids CAS number: 62304-98-7 Molecular formula: C129H215N33O55 Molecular weight: 3108.3 g/mol Format: Lyophilized material Container: Single vial Reference Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn Scientific Background Thymosin Alpha-1 was originally isolated and characterized from thymic peptide preparations. The scientific literature has subsequently examined synthetic Thymosin Alpha-1 in cellular, animal and clinical research contexts. Laboratory studies have investigated its relationship with dendritic-cell differentiation and maturation, Toll-like-receptor signalling, T-cell-associated markers and cytokine and chemokine expression. Research has also examined its role at the interface between innate and adaptive immune signalling. These areas describe experimental endpoints and research pathways. They should not be interpreted as claims that this product stimulates immunity or produces a therapeutic effect. Potential Research Areas Dendritic-cell differentiation and maturation Toll-like-receptor pathway studies T-cell signalling and differentiation models Cytokine and chemokine expression analysis Innate and adaptive immune-system communication Peptide stability and degradation studies Analytical identity and purity testing Thymosin Alpha-1 and Thymalfasin The name thymalfasin is used in pharmaceutical and clinical literature for synthetic Thymosin Alpha-1. However, published findings involving a regulated pharmaceutical preparation cannot automatically be transferred to an independently supplied research material. The identity, purity, quantity, excipients and manufacturing controls of the specific material must be evaluated using its batch documentation. This Nuforme product should not be represented as a pharmaceutical thymalfasin product. Not the Same as Thymosin Beta-4 Thymosin Alpha-1 is chemically and functionally distinct from Thymosin Beta-4 and TB-500. Although their names refer to the thymosin peptide family, they have different amino-acid sequences, molecular characteristics and areas of laboratory investigation. Analytical Considerations Researchers should review the Certificate of Analysis associated with the specific product batch. Relevant documentation may include peptide identity confirmed by mass spectrometry, purity measured by HPLC, tested material quantity, batch number, analysis date and applicable storage conditions. HPLC purity, mass-spectrometry identity and total vial quantity represent different analytical measurements. A purity percentage alone does not confirm the quantity of material contained in the vial. Storage Store the unopened vial according to the conditions stated on the product label and its batch-specific documentation. Keep the material sealed and protected from light, heat and moisture. Storage guidance from another supplier should not be assumed to apply to this product. For laboratory research only. Not for human consumption or veterinary use. This product is not a drug, medication, supplement or cosmetic and is not intended to diagnose, treat, cure or prevent any disease.
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